Some cases described the time at which the onset of symptoms occurred, and they ranged from birth to one month after birth. Blood levels were not provided, making it not possible to determine whether the events resulted from antipsychotic drug toxicity or withdrawal. Symptoms reported included agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress and feeding disorder.
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Talk to your healthcare professional if you have concerns about any treatment you are receiving during pregnancy.Abruptly stopping antipsychotic medication can cause significant complications in your treatment.
Do not stop taking your antipsychotic medication if you become pregnant without first talking to your healthcare professional.Notify your healthcare professional if you become pregnant or intend to become pregnant while taking an antipsychotic medication.In some newborns, the symptoms subside within hours or days and do not require specific treatment other newborns may require longer hospital stays. The symptoms of EPS and withdrawal in newborns may include agitation, abnormally increased or decreased muscle tone, tremor, sleepiness, severe difficulty breathing, and difficulty in feeding. Patients should not stop taking these medications if they become pregnant without talking to their healthcare professional, as abruptly stopping antipsychotic medications can cause significant complications for treatment. Healthcare professionals should be aware of the effects of antipsychotic medications on newborns when the medications are used during pregnancy. Common brand names for antipsychotic drugs include Haldol, Clozaril, Risperdal, Zyprexa, Seroquel, Abilify, Geodon, and Invega (see List of Antipsychotic Drugs below). The new drug labels now contain more and consistent information about the potential risk for abnormal muscle movements (extrapyramidal signs or EPS) and withdrawal symptoms in newborns whose mothers were treated with these drugs during the third trimester of pregnancy.Īntipsychotic drugs are used to treat symptoms of psychiatric disorders such as schizophrenia and bipolar disorder, and have been shown to improve daily functioning in individuals with these disorders. Food and Drug Administration (FDA) is informing healthcare professionals that it has updated the Pregnancy section of drug labels for the entire class of antipsychotic drugs. Additional Information for Healthcare Professionals
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